Jun 01, 2015 salivary gland cancer is a rare disease in which cancerous cells form in the tissues of the salivary glands. Each gland has its own tube duct leading from the gland to the mouth. Description the tongue, cheeks, and palate the hard and soft areas at the roof of the mouth contain many glands that produce saliva. Salivary gland cancers are named according to which of these cell types they most look like when seen under a microscope. High grade transformation in salivary gland carcinomas, a. Cancer is caused by changes in the dna inside of cells. There are several pairs of salivary glands in different locations a major pair in front of the ears parotid glands. For salivary gland cancer, an endoscope is inserted into the mouth to look at the mouth, throat, and larynx. Seroustype acini of a parotid gland with dense secretory granules histologic section of a submaxillary gland. Sep 28, 2017 although we know a few things that can raise a persons risk of salivary gland cancer, its not clear exactly what causes most of these cancers. Acinic cell carcinoma 3% of all salivary gland neoplasm 8090% in parotid 15% of all parotid tumors mean age is 4050 years 23 occur in female 3% shows bilateral involvement second most common salivary gland tumor in children well circumscribed tumor. Dna is the chemical in each of our cells that makes up our genes the instructions for how our cells function. Prognosis and survival for salivary gland cancer canadian. Still in the us, carcinomas of the major salivary glands comprise 11% of oropharyngeal neoplasms.
There are also hundreds of small minor salivary glands lining parts of the mouth, nose, and larynx that can be seen only with a microscope. Terminal branch of external carotid artery that divided into. People with salivary gland cancer may have questions about their prognosis and survival. Neoplams of salivary glands tumors of salivary glands uncommon 3% to 6% of all tumors of head. Salivary gland tumors msd manual professional edition. Pac was first proposed by evans and batsakis in 1984 as a distinct type of salivary gland carcinoma under the nomenclature of polymorphous low grade adenocarcinoma plga. Ppt salivary gland imaging powerpoint presentation. Differentiation of benign and malignant tumors is not the primary goal of ct and mri. Salivary gland tumors definition of salivary gland tumors. In children and adolescents, salivary gland tumors make up 0. Salivary gland tumors are abnormal cells growing in the gland or in the tubes ducts that drain the salivary glands.
Salivary gland tumors definition of salivary gland. An endoscope is a thin, tubelike instrument with a light and a lens for viewing. Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain com. Salivary gland tumors tehran university of medical sciences. This is the most common salivary gland malignancy 2025 per cent of all malignant salivary gland neoplasms, occurs at mucosal sites more frequently than in major salivary glands, and accounts for 26 per cent of parotid tumours and approximately 15 per cent of submandibular tumours. Salivary gland tumors after childhood radiation treatment for benign conditions of the head and neck. The cystic lesion has a mildly fibrotic appearing wall, is lined by histiocytes intermixed with rare lymphocytes, and contains mucous and macrophages. Most are located in the parotid glands and most are benign. Salivary gland tumors are rare types of tumors that begin in the salivary glands. Salivary gland tumors can begin in any of the salivary glands in your mouth, neck or throat. Longterm results are related to the grade of the cancer.
What views are acquired in the salivary gland imaging. Salivary gland tumors tumors that arise from the salivary gland may arise from the salivary epithelium the parenchyma or the supportive stroma mesenchymal benign parenchymal tumors are known as adenomas malignant tumors are known as adenocarcinomas. Radiotherapy if a salivary gland tumour is cancerous, radiation therapy may be necessary fast neutron therapy has been used successfully to treat salivary gland tumors, 11 and has shown to be significantly more effective than photons in studies treating unresectable salivary gland tumors. Use of wireless phones and the risk of salivary gland tumours. Salivary gland tumors information mount sinai new york. Cancer of the salivary glands commonly presents with one of several different histologies. Salivary gland tumors is the property of its rightful owner. Salivary gland tumors present as painless masses in the salivary glands either in front of the ear in the case of a parotid tumor, below the jaw in the case of a submandibular tumor, or in the mouth or throat in case of a sublingual or minor salivary gland tumor.
Pathogenesis and histogenesis of salivary gland tumours prezi. Mid17th century anatomy of the parotid gland and the role of the main ducts. Characterization ie, benign or malignant, and histological type, location deep or superficial. Generally, an ebook can be downloaded in five minutes or less. Definition a salivary gland tumor is an uncontrolled growth of cells that originates in one of the many salivaproducing glands in the mouth. Although we know a few things that can raise a persons risk of salivary gland cancer, its not clear exactly what causes most of these cancers cancer is caused by changes in the dna inside of cells. Salivary gland cancers malignant salivary gland tumors there are many types of salivary gland cancers. Mar 18, 2019 staging of malignant salivary gland tumors is important for predicting prognosis and for accurate comparison of treatment results. Larger the size of salivary gland, more the chance of tumor being benign. Salivary gland tumors merck manuals professional edition.
Salivary gland tumors are rare, and information on management of locoregional and metastatic disease is based on retrospective series and phase ii trials, most commonly in acc. Be able to identify parotid, submandibular and sublingual salivary glands on the basis of histological appearance and by the types of secretion produced by each gland. Risk of salivary gland cancer after childhood cancer. Only a doctor familiar with a persons medical history, type of cancer, stage, characteristics of the cancer, treatments chosen and response to treatment can put all of this information together with survival statistics to arrive at a prognosis. You have three pairs of major salivary glands under and behind your jaw parotid, sublingual and submandibular. Most small salivary gland tumors begin in the palate roof of the mouth. The sections show a stratified squamous epithelium with a thin layer of parakeratosis, minor salivary glands, and a wellcircumscribed cystic lesion. Malignant sgts represent 6% of head and neck cancers and 0. Salivary cancers form in tissues of salivary glands in the floor of the mouth and throughout the oropharynx, the parotid glands, and the submandibular glands. Neither was there an increased risk for the different phone types when calculated separately nor was there an increased risk for different latencies or when cumulative use was divided into. The use of wireless phones was not associated with an overall increased risk of salivary gland tumours, odds ratio 0. Being exposed to certain types of radiation may increase the risk of salivary cancer. Minor salivary glands netherland cancer institute, 2000 retrospective.
Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. The salivary glands make saliva and release it into the mouth. How much na 99mtco4 pertechnetate should be administered to the patient. Activity of chemotherapy in the palliative treatment of salivary gland tumors. Normal salivary glands are made up of many different kinds of cells, and tumors can start in any of these cell types. Use of wireless phones and the risk of salivary gland. The majority of these neoplasms are benign 80% and only 20% are malignant. Mortality from malignant salivary gland neoplasms varies by stage and pathology, but the overall 5year survival rate is 72%.
Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Their complexity is attributed to heterogeneity of the cells of. Mar 18, 2019 salivary gland neoplasms most commonly appear in the sixth decade of life. Ppt salivary gland tumors powerpoint presentation free to download id. For malignant tumors, treatment is with excision and radiation. The american joint committee for cancer staging and end result reporting ajcc has published a tumor, node, and metastases tnmbased staging system for major salivary gland malignancies. A painless salivary mass is the most common sign and is evaluated by fineneedle aspiration biopsy. Diagnosis of diseases of the large salivary glands of the head by ultrasound, sialography and ctsialography. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours. Acinic cell carcinoma 3% of all salivary gland neoplasm 8090% in parotid 15% of all parotid tumors mean age is 4050 years 23 occur in female 3% shows bilateral involvement second most common salivary gland tumor in children well circumscribed tumor with fibrosis tissue macroscopically. Most salivary gland tumors are benign and occur in the parotid glands. The three main pairs of salivary glands are the parotid glands, the sublingual glands, and the submandibular glands. Salivary glands make saliva, which aids in digestion, keeps your mouth moist and supports healthy teeth.
Salivary gland tumors are one of the most complex and relatively rare group of lesions encountered in oral pathology practice. Greeks called paraauricular swellings described findings associated wi. Salivary gland tumors symptoms and causes mayo clinic. The incidence of salivary gland neoplasms as a whole is approximately 5.
Dec, 2018 salivary cancers form in tissues of salivary glands in the floor of the mouth and throughout the oropharynx, the parotid glands, and the submandibular glands. Be able to identify striated ducts of the salivary gland at the light and electron microscope level and correlate the structural features of the constituent cells to the. The various types of salivary gland tumors are best distinguished by their histologic patterns. Oct 26, 2018 you have three pairs of major salivary glands parotid, sublingual and submandibular. They produce saliva, which moistens food to help with chewing and swallowing. Saliva has enzymes that help to digest food and antibodies that help protect against infections of the mouth and throat. Salivary gland tumors are benign, or noncancerous growths that are often removed without further need. Benign and malignant diseases of salivary glands 1. Salivary gland tumors sgts are rare neoplasms accounting for 0.
An approach to the why is salivary gland pathology. Winner of the standing ovation award for best powerpoint templates from presentations magazine. Ppt salivary gland tumors powerpoint presentation free. Important structure that run through the parotid gland. What is the method of localization of the salivary glands. Salivary gland neoplasm an overview sciencedirect topics. If so, share your ppt presentation slides online with. More than half of all salivary gland tumors are benign not cancerous and do not spread to other tissues. Salivary gland tumors ppt by dr gulzar a bhat authorstream. Salivary gland cancer is a type of head and neck cancer. Patients with malignant lesions typically present after age 60 years, whereas those with benign lesions usually present when older than 40 years. Introduction salivary glands major parotid submandibular sublingual minor.
However, if chemotherapy improves survival is unknown. Investigations such as fine needle aspiration cytology and mri scans provide some useful information, but most cases will require surgical excision as. Sep 28, 2017 salivary gland cancers malignant salivary gland tumors there are many types of salivary gland cancers. Ppt salivary gland tumors powerpoint presentation free to. Salivary gland neoplasms make up 6% of all head and neck tumors. An mri or ct scan can also show whether metastasis has occurred. Chemotherapy is sometimes used as palliation for patients with salivary gland tumors not amenable to curative treatment. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Portion of a parotid gland demonstrating multiple foci of sebaceous differentiation. The overall incidence of salivary gland tumors varies around the world from approximately 0. We usually look like our parents because they are the source of our dna. The high grade carcinoma exhibits marked nuclear atypia with prominent nucleoli, frequent mitoses, and comedotype geographic tumor necrosis n.
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